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Application of Kaiser Sepsis Calculator in culture-positive infants with early onset sepsis 
 
Application of Kaiser Sepsis Calculator in culture-positive infants with early onset sepsis
  Gretchen Kopec, Marc Collin, Anirudha Das
 [Abstract] [Full Text] [PDF]   Pageviews: 1800 Times
 
Background: Kaiser Sepsis Calculator (KSC) reduces antibiotic use, testing and intravenous infiltrates but there are concerns about the missed early onset sepsis (EOS) cases. We sought to apply the KSC score for culture-positive infants retrospectively in infants born in the last 10 years in our hospital.
Methods: In a retrospective cohort study, the comparison groups were divided into Group A (no antibiotics recommended by KSC) and Group B (antibiotics recommended).
Results: Overall, 17/24 (71%) infants would have been started on antibiotics per KSC but 7/24 (29%) would not. The initial EOS risk was not significantly different between the groups (Group A vs. Group B: 0.44 vs. 0.76, P = 0.41), but the final risk score was (0.33 vs. 9.41, P < 0.001). In Group A (no antibiotics), 3/7 infants became symptomatic between 9 and 42 hours.
Conclusion: There may be a potential delay in starting antibiotics in infants that are asymptomatic at birth while using KSC.
 
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World Journal of Pediatric Surgery

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