Ming Liu, Yu-Zhen Zhang, Yu-Hua Li, Hua Xie

Shanghai, China

Author Affiliations: Department of Radiology, Xin Hua Hospital Affiliated to Shanghai Jiaotong University, Shanghai 200092, China (Liu M, Zhang YZ, Li YH); Department of Radiology, Xin Hua Hospital Affiliated to Shanghai Jiaotong University, Shanghai 200092, China (Xie H)

Corresponding Author: Ming Liu, MD, Xin Hua Hospital Affiliated to Shanghai Jiaotong University, Shanghai 200092, China (Tel: 86-21- 65790000 ext 5003; Email: lesserniuniu@126.com)

Background: We described the clinical and imaging manifestations of eosinophilic cystitis and eosinophilic granulomatous cystitis in children.

Methods: The clinical and imaging (mainly CT) manifestations of 7 patients with pathologically proved eosinophilic cystitis and 2 patients with eosinophilic granulomatous cystitis were analyzed retrospectively after cystoscopic tissue biopsy or surgery.

Results: Six boys and three girls, aged 3-13 years (mean 8.3 years), complained of hematuria, irritative voiding, dysuria and abdominal pain. CT scans showed localized or nodular lesions in 4 patients, 2 of them had proved eosinophilic granulomatous cystitis, and others had diffused lesions. All patients were subjected to  bladder autoaugmentation, mass resection or medication with corticosteroids and antibiotics.

Conclusions: The clinical and imaging (mainly CT) manifestations of eosinophilic cystitis and eosinophilic granulomatous cystitis in children are apt to be confused with other bladder tumors. Biopsy is necessary for confirming the diagnosis of the lesion and to select the proper management.

Key words: bladder; tumor; cystitis; eosinophils; biopsy; computed tomography

                    World J Pediatr 2007;3(3):222-225