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Sleep disordered breathing in children with achondroplasia 
 
Sleep disordered breathing in children with achondroplasia
  Marco Zaffanello, Gaetano Cantalupo, Giorgio Piacentini, Emma Gasperi, Luana Nosetti,
 [Abstract] [Full Text] [PDF]   Pageviews: 4680 Times
 
Background:
Children with achondroplasia often have breathing problems, especially during sleep. The most important treatments are adenotonsillectomy (for treating upper obstruction) and/or neurosurgery (for resolving cervicomedullar junction stenosis).
Data sources:
We reviewed the scientific literature on polysomnographic investigations which assessed the severity of respiratory disorders during sleep.
Results:
Recent findings have highlighted the importance of clinical investigations in patients with achondroplasia, differentiating between those that look for neurological patterns and those that look for respiratory problems during sleep. In particular, magnetic resonance imaging (MRI) and somatosensory evoked potentials are the main tools to evaluate necessary neurosurgery and over myelopathy, respectively.
Conclusions:
The use of polysomnography enables clinicians to identify children with upper airway obstruction and to quantify disease severity; it is not suitable for MRI and/or neurosurgery considerations.
 
Key words: achondroplasia; children; polysomnography; sleep disordered breathing; upper respiratory tract obstruction
 
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World Journal of Pediatric Surgery

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