Quick Search
  Home Journal Information Current Issue Past Issues Services Contact Us  
Articles
Vascular dysfunction of postural tachycardia syndrome in children 
 
Vascular dysfunction of postural tachycardia syndrome in children
  Wei Bai, Si-Yao Chen, Hong-Fang Jin, Jun-Bao Du
 [Abstract] [Full Text] [PDF]   Pageviews: 1128 Times
 
Background: Postural orthostatic tachycardia syndrome (POTS) is a form of orthostatic intolerance, and its incidence in children is approximately 6.8% [ 1 ]. The pathogenesis of POTS is complex with multiple, overlapping, interacting pathophysiological mechanisms. Although the specific pathogenic mechanism has remained perplexing, with the discovery of various gasotransmitters and biological peptides, the vascular dysfunction has aroused overwhelming attention.
Data sources: On the basis of searching in a wide range of recent original literatures, we reviewed the pathogenesis of vascular dysfunction in children with POTS.
Results: The flow-mediated vasodilation of POTS patients was greater than that of healthy controls, and the vasodilator factors were increased in patients with POTS under basal condition or under a standing position, while the vasoconstriction factors were reduced.
Conclusions: Vascular dysfunction, as one of pathogenesis in pediatric POTS patients, aff ects the occurrence and development of diseases through a variety of factors.
 
  [Articles Comment]

  title Author The End Revert Time Revert / Count

  Username:
  Comment Title: 
 
   

 

     
 
     
World Journal of Pediatric Surgery

roger vivier bags 美女 美女

Home  |  Journal Information  |  Current Issue  |  Past Issues  |  Journal Information  |  Contact Us
Children's Hospital, Zhejiang University School of Medicine, China
Copyright 2007  www.wjpch.com  All Rights Reserved Designed by eb